Transitioning out of Open Access: A Closer Look at Institutions for Management of Groundwater Rights in France, California, and Spain

[EN] Many regions around the world are transitioning out of open access to groundwater resources in order to tackle over extraction by irrigated agriculture. However, the state has limited capacities to regulate effectively agricultural groundwater use. This paper evaluates how users and public authorities can co-manage groundwater extraction by agriculture. Based on Schlager and Ostrom¿s ¿bundle of rights¿ framework, the paper examines how decisions over access and use of groundwater resources are made in France, Spain and California. The three cases share a common strive to involve groundwater users in decisions over how to reduce over extraction of groundwater resources. However, different choices were made regarding the institutional set-up for user involvement in allocation decisions. The paper presents the diversity of institutional arrangements influencing groundwater allocations in the three cases, and the relative involvement and power of users and public authorities over these institutions. The papers show the different ways in which ¿comanagement¿ may be made operational for managing agricultural groundwater use.This research benefited from funding of the EU H2020 RURECO project (grant agreement 750553) and from Montpellier University I-Site MUSE. This study has also received funding from the eGROUNDWATER project (GA n. 1921), part of the PRIMA programme supported by the European Union's Horizon 2020 research and innovation programmeRouillard, J.; Babbitt, C.; Pulido-Velazquez, M.; Rinaudo, J. (2021). Transitioning out of Open Access: A Closer Look at Institutions for Management of Groundwater Rights in France, California, and Spain. Water Resources Research. 57(4):1-20. https://doi.org/10.1029/2020WR028951S12057

Participatory analysis for adaptation to climate change in Mediterranean agricultural systems: possible choices in process design (versão Pre Print)

There is an increasing call for local measures to adapt to climate change, based on foresight analyses in collaboration with actors. However, such analyses involve many challenges, particularly because the actors concerned may not consider climate change to be an urgent concern. This paper examines the methodological choices made by three research teams in the design and implementation of participatory foresight analyses to explore agricultural and water management options for adaptation to climate change. Case studies were conducted in coastal areas of France, Morocco, and Portugal where the groundwater is intensively used for irrigation, the aquifers are at risk or are currently overexploited, and a serious agricultural crisis is underway. When designing the participatory processes, the researchers had to address four main issues: whether to avoid or prepare dialogue between actors whose relations may be limited or tense; how to select participants and get them involved; how to facilitate discussion of issues that the actors may not initially consider to be of great concern; and finally, how to design and use scenarios. In each case, most of the invited actors responded and met to discuss and evaluate a series of scenarios. Strategies were discussed at different levels, from farming practices to aquifer management. It was shown that such participatory analyses can be implemented in situations which may initially appear to be unfavourable. This was made possible by the flexibility in the methodological choices, in particular the possibility of framing the climate change issue in a broader agenda for discussion with the actors

Utilidad de la resonancia magnética avanzada para la aproximación diagnóstica preoperatoria en gliomas

INTRODUCCIÓN: Los tumores cerebrales son lesiones de gran diversidad histológica y genética, de ellos los gliomas son el grupo más frecuente. Los avances imagenológicos enfocados en la resonancia magnética avanzada y funcional, así como la categorización genética han permitido mejorar el enfoque terapéutico de estos pacientes, pero sin cambios significativos en el pronóstico. OBJETIVO: Reconocer la capacidad de la Espectroscopía, Perfusión y Difusión para el diagnóstico preoperatorio sobre las características histopatológicas e inmunohistoquímicas de las lesiones ocupantes de espacio de origen glial. MATERIAL Y MÉTODO: Se aplicaron técnicas de resonancia magnética avanzada (Espectroscopia - Perfusión - Difusión) a los pacientes con lesiones ocupantes de espacio en SNC con diagnóstico histopatológico de gliomas. Se correlacionaron estos resultados con el análisis histopatológico e inmunohistoquímico de las piezas quirúrgicas. Se revisó la asociación de estos índices imagenológicos (Índice Cho/Cr-Cho/NAA-NAA/Cr-DWI-rCVB) con la histología y la inmunohistoquímica en relación al índice de replicación celular de estas lesiones (anticuerpo KI 67) RESULTADOS: Se evidenció una relación entre aumento de índices de espectroscopia (Cho/Cr y Cho/NAA) e índices de difusión (DWI) y su relación con KI67/MIB1 en tumores de alto grado. DISCUSIÓN: Si bien los resultados no pueden probarse de forma estadística debido al tamaño de la muestra se puede evidenciar asociación entre hallazgos imagenológicos preoperatorios con características genéticas tumorales de forma preoperatoria. CONCLUSION: Las técnicas imagenológicas han avanzado en forma significativa en las últimas décadas, pero poco se ha logrado influir en el pronóstico de pacientes con lesiones gliales del SNC. La posibilidad de conocer en una etapa preoperatoria de las características histológicas e inmunohistoquímicas de los tumores primarios del SNC podría ser de gran ayuda en el abordaje interdisciplinario de estas lesiones

Inter-basin transfers as a supply option: the end of an era?

International audienceThis chapter discusses the evolving role of interbasin transfers (IBT) in urban water management. After providing an historical overview of IBT development, the chapter describes how IBTs are challenged by a change in the technological and socio-economic context. The emergence of alternative technologies, such as desalination, wastewater reclamation and reuse, or managed artificial groundwater recharge is reducing the attractiveness of IBTs. Water utilities are also becoming increasingly aware that water conservation programs can save volumes of water at a much cheaper cost than IBT. Various international examples are used to show that IBTs trigger increasing concerns from communities involved or affected, in particular related to the environmental impact on donor and receiving river basins, the economic impact on donor regions, the impact on local cultures and livelihoods, how costs and benefits are distributed (social justice), and issues related to public participation. The chapter concludes by looking ahead at new and more efficient uses of existing IBTs. As conjunctive use management approaches gain support, IBTs will be operated in conjunction with aquifer storage and recovery schemes. They will probably also support the development of emerging water markets, in particular during drought years

Spatial mapping of flow-induced molecular alignment in a noncrystalline biopolymer fluid using double quantum filtered (DQF) 23Na MRI

Flow-induced molecular alignment was observed experimentally in a non-liquid- crystalline bioplymeric fluid during developed tubular flow. The fluid was comprised of rigid rods of the polysaccharide xanthan and exhibited shear-thinning behavior. Without a requirement for optical transparency or the need for an added tracer, 23Na magic angle (MA) double quantum filtered (DQF) magnetic resonance imaging (MRI) enabled the mapping of the anisotropic molecular arrangement under flow conditions. A regional net molecular alignment was found in areas of high shear values in the vicinity of the tube wall. Furthermore, the xanthan molecules resumed random orientations after the cessation of flow. The observed flow-induced molecular alignment was correlated with the rheological properties of the fluid. The work demonstrates the ability of 23Na MA DQF magnetic resonance to provide a valuable molecular-mechanical link

DOCUMENTATION FOR ENVIRONMENTAL RISK ASSESSMENT AND MITIGATION OF BUILT CULTURAL HERITAGE IN CENTRAL ASIA: THE ERAMCA PROJECT

The ERASMUS+ initiative funded, in 2019, a Capacity Building project named ERAMCA (Environmental Risk Assessment and Mitigation in Central Asia) to build up a study plan at the Master of Science level (120 ECTS in 2 academic years) open to Architects, Civil, Building, and Environmental Engineers to build-up a new generation of professionals able to work in a team with different specialities to document Cultural Heritage assets by considering environmental risks. These new professionals will be able to set up the helpful basic knowledge to plan future actions of preservation and enhancement by following the most recent development in the restoration field at the international level.The ERAMCA project started with a survey of the basic knowledge of architects and engineers in Uzbekistan and Tajikistan on the documentation of natural and anthropic risks.By considering the common knowledge, the Partners of the ERAMCA project (3 European Universities from Italy, Germany, and Croatia and 4 Universities from Uzbekistan and Tajikistan) realised a study plan by concentrating the teaching activity on the following disciplines: Geomatics, Restoration, Structure and Seismic Engineering, Hydrogeology and Geotechnics.ERAMCA project is in its last year of activity, and the final results can be presented and discussed among the Cultural Heritage Documentation community to offer possible suggestions for future actions to diffuse documentation strategies.</p

Group B Streptococcus pilus sortase regulation: a single mutation in the lid region induces pilin protein polymerization in vitro

Gram-positive bacteria build pili on their cell surface via a class C sortase-catalyzed transpeptidation mechanism from pilin protein substrates. Despite the availability of several crystal structures, pilusrelated C sortases remain poorly characterized to date, and their mechanisms of transpeptidation and regulation need to be further investigated. The available 3-dimensional structures of these enzymes reveal a typical sortase fold, except for the presence of a unique feature represented by an N-terminal highly flexible loop known as the "lid." This region interacts with the residues composing the catalytic triad and covers the active site, thus maintaining the enzyme in an autoinhibited state and preventing the accessibility to the substrate. It is believed that enzyme activation may occur only after lid displacement from the catalytic domain. In this work, we provide the first direct evidence of the regulatory role of the lid, demonstrating that it is possible to obtain in vitro an efficient polymerization of pilin subunits using an active C sortase lid mutant carrying a single residue mutation in the lid region. Moreover, biochemical analyses of this recombinant mutant reveal that the lid confers thermodynamic and proteolytic stability to the enzyme

Search for charginos in e+e- interactions at sqrt(s) = 189 GeV

An update of the searches for charginos and gravitinos is presented, based on a data sample corresponding to the 158 pb^{-1} recorded by the DELPHI detector in 1998, at a centre-of-mass energy of 189 GeV. No evidence for a signal was found. The lower mass limits are 4-5 GeV/c^2 higher than those obtained at a centre-of-mass energy of 183 GeV. The (\mu,M_2) MSSM domain excluded by combining the chargino searches with neutralino searches at the Z resonance implies a limit on the mass of the lightest neutralino which, for a heavy sneutrino, is constrained to be above 31.0 GeV/c^2 for tan(beta) \geq 1.Comment: 22 pages, 8 figure

Evaluation of a Mixed Meal Test for Diagnosis and Characterization of PancrEaTogEniC DiabeTes Secondary to Pancreatic Cancer and Chronic Pancreatitis: Rationale and Methodology for the DETECT Study From the Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer

Pancreatogenic diabetes mellitus is most commonly the result of chronic pancreatitis but can also occur secondary to pancreatic cancer. The early identification of pancreatogenic diabetes and distinction from the more prevalent type 2 diabetes are clinically significant; however, currently, there is no validated method to differentiate these diabetes subtypes. We describe a study, "Evaluation of a Mixed Meal Test for Diagnosis and Characterization of PancrEaTogEniC DiabeTes Secondary to Pancreatic Cancer and Chronic Pancreatitis: the DETECT study," that seeks to address this knowledge gap. The DETECT study is a multicenter study that will examine differences in hormone and glucose excursions after a mixed meal test. The study will also create a biorepository that will be used to evaluate novel diagnostic biomarkers for differentiating these diabetes subtypes